There are four primary types of uncertainty in health economic modelling:
- Heterogeneity: Variation between individuals that can be explained by their characteristics
- Stochastic uncertainty: Variation between individuals that cannot be explained by their characteristics,
- Parameter uncertainty: Uncertainty in the estimated values for the parameters that define the model
- Structural uncertainty: Uncertainty in model outcomes that arise from assumptions and decisions made in the modelling process.
You can learn more about these types of uncertainty in the R for Health Technology Assessment textbook.