Multiple sclerosis patient treatment preferences and health outcomes

Who knows best, patients or physicians? Clearly, physicians have medical knowledge that patients do not. On the other hand, patients have their own preferences balancing treatment safety, efficacy, convenience and other factors. Further, physicians may be more familiar with older less effective treatments compared to newer more effective treatments. One interesting question is how health…

What is the best way to predict medication adherence? Logistic vs. LASSO vs. random forest

Let’s say you are studying patients taking Drug A for Disease X. Further assume that you want to identify predictors that a patient is adherent to Drug A. Using health insurance claims data, you define your outcome–medication adherence–as whether the patient had proportion of days covered (PDC) is greater than or equal to 80%, the…

Coronavirus lands in the US

Today, the first case of coronavirus was identified in the U.S. The man was infected when he traveled to visit relatives in the Wuhan, China. Here are some helpful FAQs. Where has the coronavirus spread? The CDC website reports: Chinese authorities first identified the new coronavirus, which has resulted in close to 300 confirmed human…

Synthetic Control Method

One popular technique for causal inference is difference-in-difference (DiD) estimation. Under DiD, there is one cohort of observations with both a pre and post intervention time period and another group that was not exposed to the intervention. The time trend of the group without an intervention in essence serves as a control group for the…