How should we define “unmet need”?

Many health technology assessment (HTA) agencies give additional consideration to treatments if there is unmet need. But what really defines unmet need?  According to an article by Vreman et al. (2019), there are three key elements.  First, there should be no or limited treatment alternatives.  If there are lots of good treatment options available, then…

Winning the fight against tuberculosis

Tuberculosis (TB) kills the most people in the world of any other pathogen. While treatments are available to fight TB, there are a number of challenges. First, many individuals may have latent TB where the disease may be contagious before symptoms are apparent. Second, the spread of HIV has also been problematic for controlling TB,…