Would delinking PBM reimbursement from rebates save money?

According to a Health Affairs Scholar paper by Geoffrey Joyce out this month, the answer is ‘yes’. He writes: Most PBM contracts tie their compensation to a percentage of a drug’s list price, creating a financial incentive to favor high-cost, high-rebate drugs on plan formularies at the expense of lower-cost generics and biosimilars. Furthermore, the…

Suggested Reading

Meyer and Wyse: “Medicaid Expansion Reduced Mortality” Cannon response: “If…[Medicare and Medicaid]…were drugs, regulators would pull them from the market” and “Randomized Controlled Trials of Medicare and Medicaid, Please” L.A. Times to use the Green Bay Packers ownership model? Obesity: Diet > Exercise Privacy laws for brain data.

Impact of NIH Funding Cuts on Drug Development

Last week, the Congressional Budget Office (CBO) released a report titled “How Changes to Funding for the NIH and Changes in the FDA’s Review Times Would Affect the Development of New Drugs.” The report evaluates two scenarios: A permanent 10 percent reduction in the amount of funding that the government provides to the NIH, and…

A deeper dive into drug revenue and cost

Many people don’t understand why pharmaceuticals cost so much money. Don’t pharmaceutical companies make a lot of money? The answer is ‘yes’, but only if the drugs are successful. A paper by Wouters et al. (2024) found that: Based on data for 361 of 558 new therapeutic agents approved over the study period (median follow-up…

What’s in the UK’s Life Sciences Sector Plan?

Yesterday, the UK government released it’s Life Sciences Sector Plan (LSSP). The British government summarized the provisions as follows: 1. Unlocking NHS data to find new cures. Up to £600 million investment to build the world’s most advanced health data system – helping scientists develop better treatments faster. 2. Speeding up clinical trials. Cutting red…

The increasing health and economic cost of natural disasters

On this blog we most often talk about health care issues related to chronic and acute conditions, health behaviors and public health. However, there is another dimension that is vital to health: avoiding natural disasters. Unfortunately, natural disasters appear to having an increasing impact in the US across the past decades. Between 1980-2024, 16,941 people…