NICE’s new Severity Adjustment

In the United Kingdom, the National Institute for Health and Care Excellence (NICE) made an update to their health technology evaluations manual in January 2022. Of particular interest, section 6.2 of the manual states that the review committee “will consider the associated absolute and proportional QALY shortfall.”  The committee defined QALY shortfall two ways: Absolute…

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AHIP: Hospital price hikes. PBM prices for brand vs. generics.  Accuracy of Medicare vs. Medicaid claims data. Progress on hospital interoperable data sharing. HDHP and delays in hernia surgery. HPV vaccination rates fall during pandemic.  footBayes R package. Selection bias from delayed study entry in clinical genomic studies.

Societal value of disease modifying therapy for Alzheimer’s disease

Most health technology assessment (HTA) bodies measure treatment value as benefits from reduced patient morbidity and mortality and weigh these health gains against incremental changes in treatment cost. The limitation of this approach, however, is that it may ignore broader societal value. For instance, if patients have improved functional status, caregiver time and cost burden…