Direct and Indirect Effects of COVID-19 Vaccine

Clinical trials focus in-sample (direct) effect of vaccines on health outcomes (e.g., decrease in illness, hospitalization, emergency department use, and death). Typically, however, clinical trials do not test whether the vaccines reduce transmission. FDA do not require this as it would be logistically challenging and costly to estimate indirect effects of vaccination within a clinical…

What are rural emergency hospitals?

Rural Emergency Hospitals (REHs) are a new Medicare provider type created to preserve essential emergency and outpatient access in rural communities where low inpatient volume makes full-service hospitals financially unsustainable. They receive enhanced outpatient payments and a fixed monthly facility payment in exchange for forgoing acute inpatient care.​ CMS has an REH fact sheet that…

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FDA Qualifies First AI Drug Development Tool in MASH. No impact of Medicaid on crime rates. “The life of an artist is…” Elasticity of disability insurance (DI) takeup to DI generosity: 1.26 Do it anyway.

The rise of concierge medicine

From Zhu et al. (2025) in Health Affairs: Primary care clinicians have expressed growing interest in concierge and direct primary care practices, which often feature smaller patient panels and greater clinical autonomy compared with traditional primary care models. We assessed practice and workforce characteristics using a national sample of concierge and direct primary care practices…

2025 Books of the Year

As I do every year, here are the books I read and enjoyed this year. Non-fiction. How to Read a Book: The Classic Guide to Intelligent Reading by Mortimer Adler. This is probably not the most ‘fun’ book I read for the year, but it is the one that is likely to have the biggest…

How do CMS negotiated prices compare to value?

That is the question asked in a recent Health Affairs Forefront article by Peter Neumann, Josh Cohen, Sean Sullivan and Feng Xie. They compare the CMS negotiated prices for Initial Price Applicability Year (IPAY) 2027 against value-based prices (using QALYs) from the Tufts Cost-Effectiveness Analysis (CEA) Registry. The authors found that cost-effectiveness estimates varied among…