Links

FDA’s START program for gene therapies for rare disease. Impact of retirement on health behaviors. COVID impact on health care workers: reduced altruism? ICER solution to IRA’s elimination of QALYs? evLYG. Ghost therapists. Interview with Katalin Karikó.

CMMI programs increased Medicare spending

That is the finding from a recent report from the Congressional Budget Office (CBO) on the activities of the Centers for Medicare and Medicaid Innovation (CMMI) CBO previously estimated that CMMI’s activities would reduce net federal spending but now estimates that they increased that spending during the first 10 years of the center’s operation and will…

mRNA vaccine pioneers win the Nobel Prize

The 2023 Nobel Prize in Physiology or Medicine went to Katalin Karikó and Drew Weissman. The prizewinner’s work lead to the development of COVID-19 vaccines which averted millions of deaths worldwide. The Nobel Prize press release describes the scientific breakthrough in more detail: Karikó and Weissman noticed that dendritic cells recognize in vitro transcribed mRNA as a…

AI and drug discovery

As reported in the Economist: In 2019, scientists at the Massachusetts Institute of Technology (mit) did something unusual in modern medicine—they found a new antibiotic, halicin. In May this year another team found a second antibiotic, abaucin. What marked these two compounds out was not only their potential for use against two of the most…