ICER vs. NICE

A nice (pun intended) paper by Thokala et al. (2020) compares the Institute for Clinical and Economic Review (ICER) with the National Institute for Health and Care Excellence (NICE) along 4 dimensions: structure, methods, process, and use in decision-making. While ICER and NICE methods are fairly similar, ICER is a non-governmental body without any explicit…

Does the government really need to provide financial support for COVID vaccine development?

Based on an a medRχiv working paper by Vu by et al. (2020), the answer from an analysis of other emerging infectious diseases (EIDs) is an overwhelming ‘yes’. The authors analyze hypothetical investment returns of a portfolio of 141 pre-clinical emerging infectious disease (EID) vaccine development programs across different emerging infections without a vaccine. These…