Quantifying The Value of Reduced Health Disparities: Low-Dose CT Lung Cancer Screening of High-Risk Individuals within the US

That is the title of a paper currently published (well, in pre-prints) at Value in Health. Co-authors include Jaehong Kim, Moises Marin MA, Sangeetha Ramsagar, Mark Lloyd Davies, Kyana Stewart, Iftekhar Kalsekar and Anil Vachani. The abstract is below: ObjectiveTo measure the value of increasing lung cancer screening rates for high-risk individuals and its impact…

Do first-in-class cancer drugs receive a pricing premium?

According to a paper by Miljković et al. (2023), the answer is ‘no‘. The authors examine oncology treatments with FDA approvals between 2015 and 2020 and identify average wholesale prices from Redbook. Drugs were classified into three categories: (i) first approval of a new mechanism of action compound, (ii) next-in-class approval regardless the tumor type,…

Trends in Private Equity Acquisition of Oncology Clinics

That is the topic of a recent paper Tyan, Lam and Milligan (2023). Using newly created database from financial databases combined with press releases, news sources, clinic websites, and financial 10-K reports, the authors found that: During 2003 to 2022, 724 oncology clinics (53% radiation, 32% medical, 15% multi-oncologic) became affiliated with a PE-backed platform…

Healthcare Economist on Marketplace

What are the economic consequences of the updated USPSTF recommendations to move the age for annual breast cancer screening to age 40? I was interviewed at NPR’s Marketplace Morning Report today (May 11, 2023) to help answer the question. You can listen to the episode here (the segment on breast cancer screening starts at 5:32).…

The cancer tax

An ambitious paper by Chen et al. (2023) published last week aim to estimate the economic burden of cancer across 204 countries between 2020 and 2050 . The authors find that cancer’s economic burden is equivalent to an annual tax of 0.55% of global GDP. The full results are below. The estimated global economic cost…

Single Arm Trials for FDA Drug Approvals in Oncology

These are becoming increasingly common. Agrawal et al. (2022) use data between 2002-2021, and found that FDA approved: …176 new malignant hematology and oncology indications based on single-arm trials, including 116 accelerated approvals (AAs) and 60 traditional approvals. Overall, 87 approvals (49%) were for new molecular entities or original biologics and 89 (51%) were supplemental…