More evidence that there are diminishing marginal returns to quality of life gains

Quality-adjusted life years (QALYs) are commonly used to evaluate the impact of new medical technologies on patient mortality and morbidity. However, use of QALYs Many authors have discussed the fact that standard assumptions result in utility functions that are unrealistically linear and separable, overlooking the diminishing marginal utility a fundamental property of utility functions in…

The Hidden Value of Adult Informal Care in Europe

That is the title of a paper from Costa-Font and Vilaplana-Prieto (2025). They find the the value is very large indeed. Relative to a country’s Gross Domestic Product (GDP), the value of IC [informal care] ranges between 4.2% in France and 0.85% in Germany. Such relative value declines as the country’s share of formal LTC…

Economic Value of Bronchoscopy Technologies that Improves Sensitivity for Malignancy for Peripheral Pulmonary Lesions

That is the title of my new paper in Annals of the American Thoracic Society with co-authors David Ost, Fabien Maldonado, Jaehong Kim , Moises Marin, Tony Amos, Deanna Hertz, Iftekhar Kalsekar, and Anil Vachani. The abstract is below. Rational: While previous studies have assessed the clinical or economic value of specific technologies, the economic…

Methods for Including Adverse Events in Economic Evaluations

That is the title of a great review paper by Salah Ghabri, Dalia Dawoud and Michael Drummond. They discuss that guidance on the incorporation of adverse events (AEs) into economic models has not been standardized. Nevertheless, this paper provides helpful guidance. Specifically, the paper explores: (1) the incorporation of AEs in economic decision models, (2)…

HTA and cell and gene therapy

A paper by Drummond et al. (2023) examines how health technology assessment bodies deal with the challenge of value assessment for cell and gene therapies (also known as Advanced Therapy Medicinal Products (ATMPs) in Europe). To do this the authors: …undertook i) a targeted review of the literature on the clinical and economic evidence needs…