Does AI spell the end for HEOR?

That is the title of my latest column in The Evidence Base. In this latest edition of Perspectives from the Healthcare Economist, Jason Shafrin (FTI Consulting and Mann School of Pharmacy, University of Southern California) examines how AI is beginning to reshape health economics and outcomes research (HEOR), from evidence generation and literature reviews to data analysis…

Impact of Continuous Glucose Monitoring on Clinical Outcomes and Productivity Losses Among People Living With Type 2 Diabetes Not Using Insulin From an Employer’s Perspective

That is the title of a new paper out yesterday in the Journal of Diabetes Science and Technology from my FTI colleague Marie Steele-Adjognon, along with Martha E. Shepherd, Jon Harris-Shapiro, David Hines, Abraham Lee and Yeesha Poon. The abstract is below. Background: This study evaluated the impact of continuous glucose monitoring (CGM) on health…

Quantifying the Lifetime Economic Impact of Pediatric Oral Nutritional Supplements

That is the title of a new paper published this week in Clinical Nutrition with co-authors Kyi-Sin Than, Khounish Sharma, Kirk W. Kerr, and Dhanasekhar Kesavelu. The abstract is below: IntroductionPediatric malnutrition is a significant global public health challenge, particularly in low- and middle-income countries. This study quantifies the lifetime, per-person economic impact of pediatric…

Reframing schizophrenia as a neurodevelopmental syndrome: The scientific and social imperative

That is the title of a paper published today with co-authors Arundati Nagendra (from the Schizophrenia and Psychosis Action Alliance), Raquelle Mesholam-Gately and Matcheri Keshavan (both at the Department of Psychiatry at Harvard Medical School). The abstract is here: Background Schizophrenia is traditionally classified as a serious mental illness (SMI), emphasizing chronicity and disability. However,…

Operational efficiencies of using one vs multiple bispecific antibodies for diffuse large B-cell lymphoma and follicular lymphoma in the US

That is the title of a new paper published in Future Oncology with co-authors Tara Graff,Savreet Bains Chawla,Monika Jun,Nicole Heaps,Abualbishr Alshreef,David Tybor,Donald C. Moore,Nadine Zawadzki, and Kathryn Spurrier. The abstract is below: Aim To quantify the time- and cost-savings to US oncology practices from using a single bispecific antibody (bsAb) for both relapsed/refractory (R/R) diffuse…

Payers and targeted therapy in oncology

I was quoted in a recent article in Pharmaceutical Technology titled “Targeted therapies to join chemo as oncology treatment backbone“. An excerpt is below: Though payers could theoretically prioritise chemotherapy over the use of targeted treatments due to their lower price, Jason Shafrin, senior managing director of FTI’s Center for Healthcare Economics and Policy, notes…

Pulmonary Arterial Hypertension and Cancer: Unveiling Parallels in Epidemiology, Clinical Pathways, and Therapeutic Strategies

That is the title of a paper I published today in Journal of Market Access & Health Policy with co-authors by Karim EI-Kersh, Nadine Zawadzki, Catelyn Coyle, Shurui Zhang, Dhruv Dalal, Anna Watzker, and Dominik Lautsch. The abstract is below: Pulmonary arterial hypertension (PAH) and cancer share high mortality and complex prognoses. Due to PAH’s…

Cost per responder analysis of iptacopan versus eculizumab and ravulizumab in treatment of paroxysmal nocturnal hemoglobinuria

That is the tile of my recent paper in the Journal of Medical Economics with co-authors Kyi-Sin Than, Sanjana Muthukrishnan, Jincy Paulose, Ver Bilano and Nicholas Kuypers. The abstract is below: ObjectiveParoxysmal nocturnal hemoglobinuria (PNH) is a rare and debilitating hematological disease with significant economic burden. Despite the availability of multiple therapies, there is a…