Do pharmaceuticals improve quality of life? A Bayesian answer to the question when there is missing data

Let’s say we are interested in determining whether a particular treatment improves quality of life. Common measures of quality of life include EQ-5D, SF-12, and SF-36, among others. However, a systematic review of 237 randomized controlled trials found that only 43% collected SF-12 or SF-36 measures. If you are measuring a treatment’s effect on quality…