Barriers to Fair Access

Last month, ICER released their 2023 “Assessment of Barriers to Fair Access” . The report concludes the following regarding 18 drugs evaluated. ICER defines “fair access” based on the following criteria: Cost sharing Cost sharing based on net price. Patient cost sharing should be based on the net price to the plan sponsor, not the…

Who are 340B third-party administrators?

That is the question asked by a recent paper by Nikpay et al. (2023). The authors begin by describing the magnitude of the 340B program: The 340B drug discount program is designed to lower drug costs and increase drug profits for safety-net providers, called “covered entities,” by entitling them to discounts on drugs for all…

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Generative AI for economic research. Food = medicine? Drug importation stalling in Colorado. Facts about the economy.. Worse than embarrassing for my alma mater

Why Biden’s proposed patent seizures will hurt patients

The Hill reports today that: The Biden administration is rolling out a framework to enforce the government’s march-in authorities on drugs developed with taxpayer dollars, saying if drugmakers refuse to make their products “reasonably” available, then the government is prepared to give other companies license to produce those drugs at a lower cost…. If the company refuses…

How are the stock market and quantum mechanics related?

From a Lex Fridman interview with theoretical physicist Lisa Randall. “Stocks may not achieve a precise value until they’re traded, but that doesn’t mean we can’t approximate their worth until they change hands. Similarly, electrons might not have definite properties, but they do exist. It’s true that the electron doesn’t exist as a classical object…

How do different countries negotiate drug prices?

This question is particularly relevant with the passage of the Inflation Reduction Act (IRA) and the requirement that CMS negotiate a ‘maximum fair price’ for drugs with the biggest impact on Medicare’s bottom line. A Health Affairs Forefront paper by Lin et al. (2023) compares how drug price negotiation differs between Canada, France, Germany and…

How restrictive are Medicare Advantage plans?

Now that 51% of Medicare beneficiaries are enrolled in Medicare Advantage (MA), one key question is how restrictive are MA narrow networks? While beneficiaries enrolled in Medicare fee-for-service can choose any provider, MA plans can impose restrictions on enrollee’s provider choices. Measuring how restrictive an MA plan is, however, is difficult because “restrictiveness” is a…

AI and optimal insulin dosing

Can voice-based AI help patients with diabetes move more quickly towards optimal insulin dosing? According to a Nayak et al. (2023) study out today in JAMA Network Open, the answer is yes. Question  Can a voice-based conversational artificial intelligence (AI) application help patients with type 2 diabetes titrate basal insulin at home to achieve rapid…