Estimated prevalence of undiagnosed atrial fibrillation in the United States

This paper–written with co-authors Mintu P. Turakhia, Katalin Bognar, Jeffrey Trocio, Younos Abdulsattar, Daniel Wiederkehr, and Dana P. Goldman–is now up at PLOS One.  The study abstract is pasted below. Introduction As atrial fibrillation (AF) is often asymptomatic, it may remain undiagnosed until or even after development of complications, such as stroke. Consequently the observed…

Why fighting disease is hard

Without a doubt, medicine has made tremendous gains over the last decades and even more progress when viewed across centuries.  Often to treat diseases, physicians and researchers identify a single or primary pathway that is causing the disease.  Maybe there is a gene mutation which causes an abnormality.  Maybe there is a bacteria or virus…

How doctor’s die

Although this Saturday Evening Post article comparing how physicians and patients prefer end of life treatment is from 2013, it is interesting throughout. Years ago, Charlie, a highly respected orthopedist and a mentor of mine, found a lump in his stomach. He had a surgeon explore the area, and the diagnosis was pancreatic cancer. This…

Atul Gawande on AI

Tyler Cowen has one of his “Conversations” with Atul Gawande.  The interview is interesting throughout.  Below is an excerpt from their discussion on artificial intelligence. TYLER COWEN: …How far are we from having an AI that is capable of actually doing diagnosis to people? That is, they might speak into a Skype connection, something like Watson would…

Physician Prescribing Recommendations for Themselves and for Patients

In one of my recent publications, I show that patient and physician risk preferences differ.  Patients are willing to take take treatments with more both upside and downside risk, whereas physician prescribe treatments large based on which one provides the most efficacy to the average patient. One question that remains is how do patients and physician preferences over treatments…

End of Life decisions

Netflix has a very interesting documentary on end of life decisions.  Do you put your loved one on a ventilator, extend their life, but perhaps increase their suffering?  Or do you let nature take its course, but potentially lose time you could have with your loved one.  These are not easy decisions and one that the documentary…

Drugs from the sea

My daughter recently went to the Aquarium of the Pacific in Long Beach.  Not only did she enjoy seeing all the marine life, but she learned that the oceans also help humans in many ways.  For instance, many pharmaceutical firms are looking to the ocean to see if there are compounds created by sea plants,…