Top Countries for Biotechnology Innovation

Scientific American has an article ranking countries based on how conducive they are to biotechnology innovation.  The criteria are based on what is best for biotech firms and not necessary what is best for society.  The rankings are based on the following metrics: Intellectual Property (IP) protection.  In this ranking, more IP protection is considered better.  For…

New Drugs vs. Old Drugs

New drugs are (typically) more expensive than old drugs. If a hospital decides to use the latest drug technology, this will increase costs…right?   This may not always be the case.  If new drugs are more effective than old drugs, then giving patients the new expensive drug may cuts costs in other areas (such as…

BaseCase

Let’s say that you’re interested in running a Markov model, but are not mathematically savvy.  Gijs Hubben has come up with a solution in his Basecase website.  The online software allows you to customize the drug costs, medical assessment and procedure costs associated with the disease.  If available, you can use other academic models as…

Expected Value of Perfect Information

You have just done a study comparing the cost-effectiveness of drug A and drug B.  Should you just rest on these laurels or is further research on drug B warranted.  Decision Modelling for Health Economic Evaluation claims that there are 3 criteria that should determine whether or not you decide to collect more information: The…

Physician Prescribing Behavior for NSAIDs

What determines which NSAIDs physicians prescribe? According to the Naik et al. (2009) the following six factors are the most important: Direct Marketing by Pharmaceutical Reps. Patient requests for medication, often driven by direct-to-consumer pharmaceutical advertising. Habits formed during medical school. Often, these habits are influenced by drug rep visits while the physician was in…

Adaptive Partial Drug Approval

Currently the FDA requires that drug companies conduct 3 phases in order to secure the approval of a pharmaceutical. These are: Phase I. These are smaller (20-80 participants), clinical trials which determine a drug’s safety and pharmacologic properties among healthy volunteers. Phase II. This phase tests a drug’s efficacy and optimal dosage. Typically 100-300 individuals…