How do drug prices change before loss of exclusivity?

Typically, cost effectiveness analyses assume a constant price between drug approvals and loss of exclusivity. It is not clear, however, to what extent that assumption is valid, particularly after taking into account drug price discounts and rebates. A paper by Lin et al. (2024) uses 2007-2023 data on drug prices from SSR Health to answer…

Pharma CEOs: ‘European drug prices are too low’

At least according to CEOs from Novartis, Sanofi and AstraZeneca. Reuters reports: European drugmakers are urging the EU to allow higher medicine prices, warning that without stronger investment incentives, the bloc would fall further behind the U.S., where tariff threats have triggered a wave of pharma investment announcements. AstraZeneca Chief Executive Officer Pascal Soriot said…

Are drug prices too high or too low?

This is a common question I receive, often with the implicit assumption that prices in the US are too high. One key question to consider is, what are we trying to optimize? Tyler Cowen has a very good and brief post talking about drug prices and makes the case that (i) the supply of new…

Medicare moving to reference pricing?

That is the summary takeaway I had form reviewing the 91 page CMS guidance on the Inflation Reduction Act (IRA) maximum fair price (MFP) negotiation released about 10 days ago. Below, I summarize some of the key findings. SELECTING DRUG FOR PRICE NEGOTIATION Unsurprisingly, CMS is looking for the highest cost drugs among the 10…